Multiple calcified foci in the pancreas with dilatation of the main pancreatic duct is a manifestation of chronic pancreatitis. When pancreatitis occurs, pancreatic zymogen is activated in the pancreas to form pancreatic enzymes, which will digest the pancreas and pancreatic ducts, resulting in inflammatory reactions such as congestive edema, leading to dilatation of the main pancreatic ducts; at the same time, pancreatic enzymes can also damage the peripancreatic fat and cause necrosis of adipose tissue, and calcified foci can be formed after the healing of the necrotic adipose tissue. Chronic pancreatitis is a localized or diffuse chronic inflammatory change in the pancreas, and its clinical symptoms often include persistent epigastric pain, diarrhea and dyspepsia. Treatment is anti-infective, gastrointestinal decompression, nutritional support, antispasmodic and analgesic. In addition, patients with chronic pancreatitis need to quit smoking and drinking, avoid high-fat, high-protein diets and moderate exercise. When the above terms appear in the examination, it is necessary to consult a doctor in a timely manner, under the guidance of the doctor for standardized treatment.