Small blisters on the hands are very itchy back and forth, if ringworm, you can use topical clotrimazole ointment, terbinafine ointment and other antifungal drugs; if eczema, you can use topical glycerine lotion, boric acid solution and other drugs; contact dermatitis can be used to fluoride acetate easy cream, compound dexamethasone ointment and other drugs. 1. Ringworm: is due to fungal infection caused by the hand superficial skin ringworm disease, may lead to skin with small blisters, itching and other symptoms. You can use topical clotrimazole ointment, terbinafine ointment, compound ketoconazole ointment and other antifungal drugs. 2. Eczema: Inflammatory reaction caused by internal and external stimulation of a variety of factors, may also lead to small blisters on the hands of very itchy, recurring symptoms. You can use glycerine lotion, boric acid solution, hydrocortisone ointment and other drugs to treat. 3. contact dermatitis: hand skin contact with external sensitizing substances caused by contact dermatitis, will lead to contact parts of the skin erythema, blisters, pimples, itching, etc., can also cause small blisters on the hands is very itchy, back and forth, first of all, to avoid contact with the sensitizer, you can use topical fluoride acetate easy cream, compound dexamethasone cream and other glucocorticosteroid drugs treatment. Small blisters on the hands is very itchy again and again, there may be other reasons, you need to go to the hospital to check the cause of the disease, the drug should be used under the guidance of a professional doctor, to avoid abusing the drug.