Whether the life expectancy of IgA nephropathy patients will be affected needs to be assessed according to a variety of factors such as the severity of the disease, the effect of treatment and individual differences, and cannot be generalized. The 10-year renal survival rate of IgA nephropathy is 80%~85%, and the 20-year rate is about 65%. However, there is a great individual difference, some patients have a good long-term prognosis, but some patients rapidly progress to renal failure. If the patient’s condition is mild and the individual’s physique is good, the condition will be relieved or the progression of kidney disease will be delayed after active treatment, at this time, the patient’s life expectancy may not be affected; if the patient’s condition is severe and the individual’s physique is poor, the treatment effect is not good, with the progression of the condition, the disease may be developed into uremia, and at this time, the life expectancy may be affected. Patients with IgA nephropathy are advised to go to regular hospitals for consultation in time and receive targeted treatment under the guidance of doctors.