Recently, the Department of Anesthesia and Pain of the Second Hospital cured a 68-year-old patient who suffered from severe lumbar disc herniation. The patient walked out of the hospital with a smile on his face after 10 days of hospitalization and abandoned his double crutches. The patient had been suffering from back and leg pain for more than five years, and in the past six months, her left leg cramps were so severe that she often woke up with cramps at night. Although the diagnosis of lumbar disc herniation was clear, the patient was not able to undergo radical surgery due to various reasons such as advanced age, multiple discs with different degrees of severe protrusion and heavy symptoms, which increased the invasiveness, complexity and danger of open surgery, as well as high treatment costs. He tried various physiotherapy, massage, cupping, acupuncture and other treatments in many hospitals, but the treatment was not effective. Later, he went to the pain department of the Second Municipal Hospital and was warmly received by Director You Xiaobing, who made a detailed treatment plan for him. First of all, the intravertebral environment was reasonably regulated, and intravenous infusion was used to eliminate the patient’s pain, nerve root edema and nerve protection. In order to completely eliminate the “heart disease”, the patient chose the minimally invasive interventional treatment (collagenase chemical nucleolysis) for the lumbar spine, and was discharged after 7 days with satisfaction. This minimally invasive technique has the advantages of high safety, little damage and fast recovery.