About 70%-80% of patients with advanced cancer will have pain, but not all patients with advanced cancer will be very painful, only some patients with metastasis to bone, compression of nerve roots, metastasis to liver or primary liver cancer, pain caused by involvement of liver peritoneum will be more serious and will affect patients’ sleep at night. However, such pain can be treated with three-step pain medications, such as oxycodone and morphine tablets. Moreover, doctors will adjust the medication accordingly according to the degree of pain, such as adding carbamazepine to help treat neuropathic pain and adding dexamethasone to relieve the pain caused by nerve compression. Therefore, even if the pain is more severe in the advanced stage of cancer, don’t worry too much and believe that doctors will give appropriate treatment.