Lung cancer and tuberculosis are two completely different diseases in nature. Tuberculosis is an infectious disease, while lung cancer is a malignant tumor. Clinically, the difference can be made through differential diagnosis, including the following aspects: 1. Clinical manifestations: TB manifests as an infectious symptom, such as cough, coughing sputum, coughing blood and regular fever in the afternoon. Lung cancer presents as a dry cough with fresh blood in the sputum at the initial stage and compression of nerves and invasion of tissues at the later stage; 2. Lung cancer is usually a single lesion and small metastases and burrs; 3. Pathological diagnosis: Tuberculosis requires the discovery of antacid bacilli to confirm the diagnosis. Lung cancer needs to be judged by tissue biopsy to have cancer cells.