Question: Prof. Zhu, my friend had a traffic accident half a year ago which caused a brain hemorrhage, and then he underwent a craniotomy, which caused a defect of about 5*9cm, and he would like to ask if it is feasible to use autologous bone to repair it. In response to this situation, we will introduce you to the possibility of repairing the skull with autologous bone. Clinical studies have shown that bone flap resorption is one of the main complications after autologous cranial bone repair. The incidence of bone flap resorption varies widely in the literature, with a postoperative resorption rate of 1.4%-50%, of which the rate of severe bone flap resorption is 0.8%-20%. Signs of flap resorption begin to appear on CT images 2 months after repair of the autogenous bone flap and stabilize at 18 months after repair, so follow-up is often required for at least 18 months. Cranial bone resorption has 3 manifestations on CT imaging: 1) thinning of the bone flap thickness and widening of the bone window-flap spacing; 2) decreased bone density of the bone flap; and 3) localized or extensive destruction (or lysis) of the bone flap. After resorption, the patient’s scalp performance can be the skin edge concave, revealing the shape of the skull, but also may be the bone flap floating, pressing is a fluctuating feeling, reducing or even losing the protective effect. Therefore, the application of autogenous bone is not recommended. It is reported that polyether ether ketone peek cranial bone repair, with new high science molecular peek do implant material, take embedded repair way, smooth articulation after surgery, strong resistance to hit, low rate of rejection and infection. At the same time, we carry out personalized optimal design of the material and the innovation and upgrading of the surgical technology, introduce the concept of cosmetic plastic surgery, and formulate personalized cranial bone repair and cosmetic plastic surgery plan for each patient, to ensure precise postoperative repair, the shape of the two sides of the symmetry of the natural and beautiful.