A patient inquired online about the need to repair a defect in the skull caused by a traumatic injury, which is located close to the temples and is as big as a coin. Cranial defects need to be repaired. The skull, as the protective shield of the human brain, bears the most important responsibility for life activities. As a result of various accidents, the brain tissue is vulnerable to secondary damage due to the loss of an external barrier. In order to avoid this situation, patients need to undergo cranial repair as early as possible so that the intracranial pressure can be restored to a normal and stable state as much as possible. Reducing intracranial pressure due to the dramatic daily changes in brain pressure caused by cranial defects, the continuous and constant severe damage to the brain and function. At the same time the choice of materials for cranial bone repair is very important, the current medical application of new polyether ether ketone PEEK material. the main component of PEEK is hyaluronic acid and Ebève, biocompatibility is high, the phenomenon of postoperative complications and foreign body reaction caused by the clinic is basically not. Second, PEEK has a better modulus of elasticity, and the bone plate made by 3D technology printing can be perfectly three-dimensionally shaped according to the patient’s monitoring data before the operation, which perfectly restores the original structure of the skull. Third, the strength, insulation and stability of PEEK are similar to that of autologous skull, and it will not affect the medical examination such as CT MRI in the future, and even if craniotomy is needed in the future, this material can be reused after sterilization. Advanced polyether ether ketone PEEK material can rebuild a complete closed cranial cavity environment for the patient, which can help the recovery of the corresponding nerve function, and achieve the good effect of structural integrity, perfect function and beautiful appearance.