Children’s mouth crooked side to side when talking, may be physiological factors lead to bad habits of speech, etc., may also be the existence of pathological factors that is, neurological problems, pathological factors are mainly divided into central or peripheral neurological abnormalities, etc., two considerations. 1. Physiological factors: when a child imitates an adult or develops a habitual crooked mouth when speaking, with the prolongation of time, the habit of speaking with a crooked mouth may be formed. 2. Pathological factors (1) Central nerve abnormality: if the child’s crooked mouth appears gradually and shows the trend of development, it is necessary to consider whether there is a lesion in the central nervous system, such as intracranial space occupation or tumors, etc., which can gradually compress the relevant nerves, make the neuromuscular abnormalities, and then the crooked mouth occurs. (2) Peripheral nerve abnormality: the main consideration is facial neuritis, viral or bacterial infection and other pathogens can cause facial neuritis, so that its innervated facial muscles appear abnormal manifestations, presenting the symptom of crooked mouth, in addition, it can also be accompanied by eyelids can not be closed and other symptoms. Children’s mouth crooked side to side when talking, there may also be other reasons, it is recommended to go to the hospital in time, improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.