Patchy hypodense shadow in the liver belongs to an abnormal manifestation of liver CT. It means that there is a space-occupying lesion on the surface of the liver, which may be caused by liver cysts, fatty liver, liver cancer and other diseases. 1. Liver cysts: The imaging manifestation of liver cysts is usually single or multiple hypodense shadows in the liver. Liver cysts are usually benign lesions and patients need to have regular follow-up. 2. Fatty liver: when the fat distribution on the surface of the liver is not uniform, it will lead to fat deposition, which will result in flaky low-density shadow on the surface of the liver. 3. Hepatocellular carcinoma: when the cancer cells in the liver invade the normal tissues and organs of the liver, it is also often manifested as low-density shadow of the liver. At this time, patients should raise vigilance and under the suggestion of doctors, carry out examinations of tumor markers, enhanced CT, MRI, etc., so as to make a clear diagnosis. Therefore, when flaky low-density shadows appear in the liver, the patient should actively improve the relevant examinations, make a clear diagnosis, and carry out regular treatment under the guidance of the doctor.