Digoxin belongs to the digitalis class of cardiotonic drugs, and it is recommended that patients take it in the morning, when the sympathetic nerves are most excited, which helps to control the ventricular rate, and it is recommended that patients take 0.125-0.25mg each time, once a day. If patients currently have renal impairment, it is recommended that digoxin can be taken in small doses, such as 0.125mg each time, once a day, or once every other day, which can further control the patient’s ventricular rate and improve the symptoms of heart failure. Digoxin can control the ventricular rate of patients with atrial fibrillation, after the application of beta-blockers alone, the heart rate control is not good, control with digoxin is a better choice, the representative drugs of beta-blockers are bisoprolol, metoprolol and so on.