The difference between ascending colon cancer and descending colon cancer usually has the following differences:1. Location, ascending colon cancer and descending colon cancer grow in different locations, ascending colon cancer occurs in the ascending colon, while descending colon cancer often occurs in the left half of the colon.2. Early symptoms, ascending colon cancer manifests itself in abnormal defecation, with symptoms such as blood in the bowel movement, unshapely stool, or diarrhea etc., while descending colon cancer in the early stage may show symptoms such as constipation or difficulty in defecation. 3. 3, treatment method, ascending colon cancer needs comprehensive examination first, if there is no distant metastasis, surgical resection can be adopted, if metastasis occurs, chemotherapy can be carried out first, and then surgery can be carried out after distant metastasis disappears. Surgical resection is preferred for descending colon cancer, and after surgery, pathologic examination will be done to make the next treatment plan. If it is more than stage I colon cancer, all of them need more than one month of chemotherapy, and then radiation therapy according to the lymph node metastasis.