Itchy at night after taking off the clothes all over the body may be suffering from urticaria or eczema and so on. 1. Urticaria: Urticaria is a relatively common skin disease, usually associated with contact with pollen dust mites and other allergens, the main symptom is itchy skin, the affected area will have different sizes of the wind. The main symptom is itching of the skin, and the affected area will have different sizes of wind bumps. If the patient comes into contact with the allergens after taking off his clothes at night, it may cause itching all over the body. 2. Eczema: Eczema is also a relatively common skin disease, usually associated with environmental factors, such as environmental humidity, hot and stuffy, etc., the main symptom is that the affected area has pimples as well as pimples or small blisters, etc., and there will be itching symptoms. If the indoor environment itself is humid or hot, the patient may cause itching after undressing at night. It is recommended to go to the relevant departments of professional hospitals to do the examination, to clarify the specific causes, so that targeted treatment, usually must ensure that the skin is clean and hygienic, but also to choose to wear soft and loose clothing.