Leukoaraiosis, or Behçet’s syndrome, does not require hormones when the manifestations are only localized to the mucous membranes and can be used topically; if the manifestations are severe and involve the internal organs, hormones are required. Behçet’s syndrome is a chronic autoimmune disease characterized by oral and vulvar ulcers, ophthalmia, and involvement of multiple systems. If Behçet’s syndrome only involves the oral mucosa, vulvar mucosa, manifested as oral ulcers, vulvar ulcers, the patient is not necessary to take hormones, local topical glucocorticoid ointment, such as hydrocortisone ointment, etc., and comply with the doctor’s instructions to take thalidomide treatment. If Behçet’s syndrome causes lesions in the internal organs, such as the digestive tract, nervous system, cardiovascular system, lungs, etc., the patient needs to be treated with hormones such as methylprednisolone. All of the above medications should be used under the guidance of a medical professional. It is recommended that patients with Behçet’s syndrome consult the rheumatology and immunology department in a timely manner and receive standardized treatment under the guidance of a doctor.