Drugs that kill Helicobacter pylori are usually referred to as quadruple therapy in clinical practice, i.e., a first-line treatment regimen consisting of a bismuth agent and a proton pump inhibitor in combination with two antimicrobial drugs. 1. a bismuth agent: commonly used bismuth agents include bismuth potassium citrate, bismuth pectin and other drugs. 2. A proton pump inhibitor: commonly used drugs are omeprazole, lansoprazole, pantoprazole, rabeprazole, epprazole and other drugs. 3. Antibacterial drugs: commonly used antibiotics are clarithromycin, metronidazole, amoxicillin, tinidazole, quinolone antibiotics, tetracycline, furazolidone and other drugs. Killing Helicobacter pylori requires standardized treatment and attention to review. If you are found to have H. pylori infection, you should be treated under the guidance of your doctor, do not self-medicate.