The phenomenon of early, involuntary and uncontrollable discharge of sperm during intercourse in men belongs to male sexual dysfunction, which is clinically called premature ejaculation. There are many reasons for premature ejaculation, in terms of physiology, such as men’s glans sensitivity and the number of dorsal nerves of the penis is more than ordinary people, which leads to higher sensitivity, and in the process of sexual life to the sexual impulse that arises, it will be difficult to control the phenomenon and appear early ejaculation. This situation is recommended to check the glans sensitivity first, if it belongs to the penile type of premature ejaculation, you can carry out the auxiliary alternative treatment of local medication for a period of time. Not only can it enhance men’s self-confidence in sexual life, but also can prolong the ejaculation time in the presence of objective drugs. After a period of auxiliary replacement, the sensitivity of the nerves will decrease, and it will be able to delay the ejaculation time during the later sexual life, and it is also possible to get out of the auxiliary treatment of medication. Secondly, some men are due to excessive secretion of 5-hydroxytryptamine in the human brain, which leads to the phenomenon of early ejaculation, and can apply drugs to control nerve impulses, such as dapoxetine hydrochloride or sertraline, which can play a role in slowing down the phenomenon of excessive sensitivity to psychosexual stimulation and can control the symptoms of premature ejaculation. The main reason for this is that premature ejaculation can be divided into central and penile types. When men have premature ejaculation, they should undergo a professional examination and choose a more appropriate treatment for this disease.