Itchy skin at night may be related to poor hygiene habits, dry skin and other physiological factors, or it may be caused by hives, eczema, scabies and other diseases. 1. Physiological factors: If you don’t pay attention to personal hygiene in general and don’t clean your skin at night, it may cause dirt to hide in your skin and you will have itchy skin when you sleep at night. In addition, if the daily water consumption is low, the bath water is too hot, maybe there will be dry skin, may also trigger the itchy skin at night. 2. Urticaria: The cause of urticaria may be related to food, infection and autoimmune factors. It manifests itself in the form of windy bumps and angioedema, often accompanied by itching. Urticaria can occur throughout the day or intermittently, and some patients will have nighttime flare-ups, which may be accompanied by itchy skin. 3. Eczema: The etiology of eczema is not yet clear, and may be related to genetics, immune abnormalities, systemic diseases, the environment and other factors. Patients may experience redness, papules, and intense itching, which usually worsens at night. 4. Scabies: The cause of scabies is mostly related to the human scabies mite infection of the skin, patients will appear pimples, papules and intense itching symptoms. The scabies mite is more vigorous at night, so the symptoms will be aggravated at night. There are many causes of itchy skin at night, and after eliminating physical factors, patients are advised to seek medical examination to clarify the cause.