We recently performed a selective renal artery block and laparoscopic partial nephrectomy for an elderly patient with multiple cystic kidney cancer. The patient was a male and was found to have multiple cystic lesions in the left kidney by ultrasound examination 1 year ago in an outside hospital, and was considered to have multiple cysts, but a recent MRI examination in an outside hospital showed that the left kidney was considered to have cystic occupancy, and the patient underwent renal CT examination in our hospital and was considered to have cystic renal cancer in the left kidney. The patient’s left kidney was a double artery, one artery supplied the upper middle part of the left kidney and one supplied the lower part of the kidney, and the renal occupancy was located in the middle dorsal part of the left kidney, and the tumor diameter was about 3 cm. After careful analysis of the patient’s renal vascular CT 3D imaging data, it was concluded that the blood supply of the left kidney tumor mainly came from the upper branch of the left renal artery, so we decided to perform selective renal artery block and laparoscopic partial nephrectomy for the patient. Only the upper branch of the left renal artery, which mainly supplied the tumor, was blocked during the operation. Selective renal artery block can minimize the area of renal ischemia, which is very beneficial to protect renal function. Cystic renal cancer requires special attention when separating, splitting the cystic cavity will possibly lead to tumor implantation, so it is especially important to keep the integrity of the cystic cavity. In this patient with multiple cystic occupations, the cystic tumor was carefully and carefully separated during surgery, and the fat adhering to the tumor was preserved, together with about 0.5 cm of renal tissue around the renal tumor was removed, and the defective part of the kidney was quickly sutured in layers. The postoperative pathology report was cystic renal carcinoma, and the patient has now recovered and discharged from the hospital. CT image of cystic kidney tumor Laparoscopic view of multiple cystic kidney tumors Laparoscopic specimen of cystic kidney tumor with complete resection