Lubricants do not harm the body. If a patient uses lubricant occasionally, it will not have a harmful effect on the human body, but long-term use in large quantities may cause some damage to the human body. Lubricant is a water-soluble preparation, usually in the hospital for gynecological and anal examinations and massage, lubricant will be used to facilitate the examination, moderate use of the human body does not usually have adverse effects. Clinical for perimenopausal women, amenorrhea women or elderly women, or women who have removed both ovaries in sexual life, due to their own secretions to reduce the vaginal lubrication function is reduced, vaginal dryness, sexual discomfort, and even sexual bleeding. At this time often need to use external drugs to ease, clinical often choose is lubricant. If it is often used during intercourse, there may be a problem of lubricant residue, which may lead to allergies. Moreover, prolonged use of lubricants may also lead to the possibility of vaginal dysbiosis, increasing the risk of infection and causing inflammation of the surrounding area. Therefore, it is recommended to use lubricants wisely under the guidance of a medical professional.