Cold Punch does not react with alcohol, but it is recommended that you do not drink alcohol during the medication period to prevent adverse conditions. It is recommended to start drinking alcohol after 5-7 days after stopping the medicine, because by this time the medicine in the body has been completely metabolized, and the reaction with alcohol basically does not exist, so it will not lead to allergies because of drinking alcohol. Most of the cold medicines do not react with alcohol, but if it is a bacterial cold, the need to use antibiotics must be strictly prohibited alcohol intake, especially the use of cephalosporins, quinolone antibiotics when the risk of disulfiram increased, if drinking alcohol may lead to anaphylactic shock or even life-threatening.