Fibromyalgia Syndrome (FMS) FMS is not uncommon, but is usually overlooked. The main manifestations are diffuse pain, stiffness, weakness, lack of sleep, and many specific pressure points. It can coexist with many other rheumatic diseases. Clinical features: 1, female prevalence, peak incidence 20-60 years old; 2, the main symptom is the generalized pain and stiffness, the scapular girdle muscle and pelvic girdle muscle group is the most important; 3, chronic onset, there is a gradual aggravation trend, external environmental stimuli can make the condition worse, such as strenuous activities, inactivity, lack of sleep, mental shock, weather deterioration to be, etc.; 4, other manifestations include: intestinal irritation syndrome, tension 5. Special pressure points include: suboccipital muscle attachment, anterior part of the cervical 5-7 transverse process, midpoint of the lateral border of the trapezius muscle, midpoint of the scapular ridge, 2nd rib cartilage union, 2 cm distal to the lateral epicondyle of the humerus, upper hip quadrant, posterior part of the greater trochanter, and proximal medial fat pad of the knee, totaling 9 pairs; 6, CRP, RF, and blood tests are normal; 7. It can coexist with other rheumatic diseases such as rheumatoid arthritis, osteoarthritis, and Lyme disease. Diagnosis: Refer to the 1990 ACR criteria: 1. History of widespread pain for at least 3 months, defined as: simultaneous left-sided pain, right-sided pain, pain above the waist, pain below the waist, plus medial skeletal pain. 2. There are at least 11 positive pressure points among 18 special points by acupressure; each pressure site is seen as a clinical feature (5); the acupressure force should be close to 4 kg. FMS can be diagnosed by meeting the above 2 points, and the presence of other rheumatic diseases does not exclude the existence of this disease. V. Treatment: 1. Disease education: Let patients know that the disease is not a psychological abnormality, the disease does not cause deformities, and is not life-threatening; 2. Amitriptyline (antidepressant), cyclobenzaprine hydrochloride (muscle relaxant) and triazolium, given at bedtime, help improve sleep and effectively treat FMS, but can cause anticholinergic side effects. In contrast, tricyclic antidepressants have few side effects, are well tolerated, and are more effective when given 2 hours before bedtime; 3. NSAIDs given alone are not effective unless they are used to treat their underlying disease; 4. Other treatments: psychological counseling, biofeedback, pain point closure or injection of corticosteroids and exercise therapy, etc.