There is no specific treatment for syndrome X. Anti-myocardial ischemic drugs, such as beta-blockers, bethanechol and bisoprolol, as well as nitrates and calcium channel blockers, such as diltiazem, can be used routinely to improve the endothelial function of patients with syndrome X. Trimetazidine can improve symptoms in a small percentage of patients. Other drugs such as trimetazidine, which may improve symptoms in a small percentage of patients, as well as ACEIs and statins, such as captopril and atorvastatin, can be used to improve endothelial function in this group of patients. patients with syndrome X usually have angina or angina-like conditions, and coronary angiography is often normal. The onset of the disease is associated with endothelial dysfunction or microvascular dysfunction, mostly in premenopausal women, and the electrocardiogram is often normal, but there may be some nonspecific ST-T changes, and some patients have a positive plate exercise test. Vascular ultrasound may show intimal thickening of the coronary arteries or early atherosclerosis, plaque formation, and decreased coronary flow reserve.