Palm callus refers to callus in medicine, which is a yellow or waxy yellow thickened keratinous plaque, flat or slightly elevated, thicker in the center with thin edges, firm texture, and unclear borders. There are many ways to remove callus, such as trimming, medicine, physical therapy and so on. 1. Trimming: patients can use hot water to soften the palm callus, and then use the trimming tool to trim it off slowly, but be careful to avoid hurting other skin tissues. 2. Drugs: patients can follow the doctor’s instructions to use urea, salicylic acid, vitamin A cream and other drugs to be applied to the palm callus, the drug can soften the keratin, long-term persistent use of the palm callus can be removed. 3. Physical therapy: if the callus is more serious, you can also choose to go to the hospital through the laser, liquid nitrogen freezing way to remove. There are many ways to remove palm callus, if you need to use drugs or physical therapy, it is recommended to go to the hospital in a timely manner, in accordance with the doctor’s instructions to use the above medication, do not use drugs indiscriminately, so as not to lead to adverse consequences.