Nicorandil can be taken both before and after meals, but since Nicorandil has certain gastrointestinal reactions. If patients experience gastrointestinal discomfort after taking Nicorandil before a meal, they will need to take Nicorandil after a meal. Nicorandil is a nitrate compound, an ATP-sensitive potassium channel opener, which can selectively dilate coronary arteries, increase coronary blood flow, and inhibit coronary artery spasm. Nicorandil also has the effect of inhibiting platelet aggregation. The use of nicorandil can significantly reduce the risk of cardiovascular events and improve the prognosis of patients. In clinical practice, Nicorandil can be used for the treatment of coronary artery disease and angina pectoris, and is effective for all types of angina pectoris.