Girls want to urinate at night lying down, usually due to urethral stones, urethral sphincter relaxation, urethritis, overactive bladder and other factors, need to go to the hospital for further examination to clarify the cause of the disease, you can use drugs under the guidance of the doctor or surgery and other ways to treat. 1. Urethral stones: may be due to urinary tract stones caused by strong urinary tract irritation, resulting in persistent bladder contraction, which in turn causes the phenomenon of girls lying down at night want to urinate, can be used under the guidance of the doctor urethrotomy lithotripsy and other surgical methods to treat. 2. Urethral sphincter relaxation: usually due to the urethra can be and relaxation, so that the urine accumulated in the bladder, urination by nerve reflex activity, resulting in the contraction of the urinary muscle, which caused the phenomenon of girls lying at night want to urinate, can be taken under the guidance of the doctor artificial urethral sphincter implantation and other surgical procedures to treat. 3. Urethritis: generally due to urethral inflammatory media stimulation of the urethral mucosa, caused by the phenomenon of girls lying down at night want to urinate, can be in compliance with medical advice to use amoxicillin capsules, azithromycin tablets and other drugs to treat. 4. overactive bladder: usually due to overactive bladder, resulting in bladder sensitivity, caused by the phenomenon of girls lying down at night want to urinate, can be prescribed the use of succinic acid solignacin tablets, mirabelone extended-release tablets and other drugs to treat. In daily life, you should pay attention to rest, avoid overwork, appropriate exercise, improve immunity, if you have symptoms of physical discomfort, you should go to the hospital in time, under the guidance of the physician treatment, do not blindly use their own medication.