The side effects of mastication are as follows: 1. It may have an inhibitory effect on breast development, growth and proliferation, and contains certain hormonal components that interfere with the hypothalamic pituitary gonadal axis, thus inhibiting the development of the mammary glands, and may affect the normal lactation function of women. 2. It is not good for the kidneys, because after the drug is metabolized and discharged by the kidneys, the drug may adhere to the kidney tubules and glomeruli, thus damaging these parts and destroying normal physiological functions.