Complete occlusion of the left anterior descending branch, an important vessel supplying the anterior wall myocardium, is generally life-threatening, presents with acute chest pain and requires prompt stenting. However, when chronic occlusive lesions are present, they can be asymptomatic. The coronary arteries are the blood vessels that supply blood to the heart, and there are three main branches, namely the left anterior descending branch, the circumflex branch and the right coronary artery. When the left anterior descending branch is chronically blocked, collateral circulation can be formed so that the anterior wall of the myocardium is also supplied with blood, thus producing no clinical symptoms. If the coronary arteries are acutely occluded, significant clinical symptoms such as chest pain and dyspnea are produced. When the coronary artery is chronically blocked, it is not easy to detect because there are no obvious symptoms, thus affecting the treatment. Therefore, when the left anterior descending branch of the diagnosis of complete blockage, even if there are no obvious symptoms, but also timely medical treatment, in accordance with the doctor’s advice timely implantation of coronary stents, and after the operation also need to take medication according to the doctor’s advice and pay attention to a light diet, some of the lipid-lowering drugs and antiplatelet drugs need to be lifelong use, to prevent coronary stents re-blockage. It is recommended that patients seek timely medical treatment and standardize the treatment under the guidance of doctors.