Although diabetes is not a contraindication to fat aspiration and grafting filler surgery, it can increase the risk of the procedure. Such as delayed wound healing, increased infection rate, and affected prognosis results. Therefore, it is crucial for the success of the procedure that blood sugar should be controlled and stabilized at a normal level before the procedure of fat aspiration grafting filler. If a candidate’s blood sugar is found to be too high through examination before fat aspiration grafting filler, he or she needs to go to the endocrinology department for glucose-lowering treatment first. For morbidly obese people, fat reduction through fat aspiration is important for their physiological metabolic changes, especially for diabetic patients. This is because obesity can be associated with diabetes in addition to increasing the cardiovascular burden. Not all obese individuals develop diabetes, but there is a clear correlation between insulin levels and ideal body weight. Obesity increases the demand for insulin, and there is a parallel relationship between obesity and serum insulin level. Liposuction can improve obesity (pre-diabetes) and diabetes, as well as serum insulin levels in diabetic patients. If used appropriately, it can also alleviate the condition of patients with severe diabetes. It should be emphasized that blood glucose levels should first be controlled to near normal levels prior to surgery.