Osteolysis, also known as osteolysis, is also known as ghost bone. It is a slowly developing and very destructive disease that manifests as spontaneous bone resorption and is a rare disease. It is characterized by massive localized capillary sinus and fibrous tissue proliferation in bone with osteolysis. It is more common in men than in women. It is usually seen on the concave surfaces of long bones, such as the medial border of the femoral neck, the pubic symphysis, the ribs, the clavicle and the axillary border of the scapula. X-ray examination is an important test to confirm the diagnosis of this disease. The details are as follows: The bone in the lesion shows large osteolytic bone resorption, thinning of the backbone and thinning of the cortex. The large bone resorption shows a bone defect with a sharp stump. There was residual sparse atrophic bone, no new bone, no periosteal reaction, and no soft tissue masses. The histopathological manifestations of osteolysis were nonspecific, with fibrous tissue hyperplasia, lysed and resorbed bone tissue, no osteoclasts, no bone tissue proliferation, and enlarged vascular cavities visible on light microscopy.