The hazards of tobacco The smoke of burning tobacco contains more than 4,000 known chemicals, the main harmful components include nicotine, tar, carbon monoxide, amines, phenols, alkanes and so on. Nicotine acts on the human brain and makes people dependent on tobacco, a highly addictive substance that can cause vasoconstriction, increased heart rate, increased blood pressure, damage to the lining of blood vessels, and increased atherosclerosis. A person who smokes may seem to have “nothing to do with others,” but in fact, his or her family is being harmed by passive smoking. According to the definition of the World Health Organization, passive smoking means that nonsmokers inhale the smoke exhaled by smokers for more than fifteen minutes a day for more than one day a week. In China, 71% of homes, 32.5% of public places and 25% of workplaces are affected by people who ” The “swallowing and puffing” of smoke makes them passive smoking places. Many smokers eventually decide to quit, not only for personal health reasons, but also because of the dangers of secondhand smoke. Tobacco Withdrawal Syndrome The essence of withdrawal symptoms is nicotine dependence and psychological dependence. Tobacco dependence is a clearly defined neuropsychiatric disorder in which repeated intake of nicotine from tobacco causes changes in the neural pathways of the brain, resulting in a strong desire to smoke when quitting, a desire that can weaken or even destroy the quitter’s resolve. Tobacco dependence is divided into physical dependence and psychological dependence. Irritability, irritability, anxiety, depression, lack of concentration, insomnia or sleep disturbance, decreased heart rate, increased appetite, headache, dry mouth, cough and phlegm, tingling sensation, diarrhea or constipation, etc. are all withdrawal symptoms after stopping smoking. Psychological dependence is characterized by a strong craving for tobacco. Tobacco dependence is a chronic relapsing disease that must be treated with medication. Nicotine replacement therapy (NRT) Four of the first-line adjuncts to smoking cessation recommended by the WHO are nicotine replacement drugs. Nicotine replacement therapy, i.e., the use of nicotine replacement while stopping smoking, is primarily a non-tobacco form that partially provides the nicotine originally obtained from tobacco to relieve withdrawal symptoms and reduce the desire to smoke, and should be phased out once smoking cessation is achieved. Nicotine replacement therapy has been shown to be an effective treatment for smoking addiction, reducing withdrawal symptoms, lowering relapse rates, and increasing the success rate of smoking cessation.