Pain in the sternum is more likely to be caused by thoracic disease. The common symptoms are localized pain, which can be confirmed by CT examination. Some patients have malignant lesions of the thymus or mediastinum, and with the development of the disease, they may also develop thoracic deformity, which may manifest as localized bulging of the sternum, or they may have chest tightness, shortness of breath, or severe dyspnea. Reflux esophagitis may also manifest as pain in the inner chest or behind the sternum with a distinct burning sensation and worsening symptoms after eating. The elderly patients occur more often, they should pay attention to diet, sleep in a high semi-recumbent position, and apply appropriate drugs to protect the mucosa of the gastrointestinal tract, commonly used drugs are omeprazole dispersible tablets, and also oral cimetidine.