There are three main possibilities for nipple pain, as follows: first, nipple trauma, with a clear history of trauma, when external forces acting on the nipple local, can cause nipple tissue congestion, edema, acute inflammatory reaction, nipple pain. Second, cystic hyperplasia of the breast, mostly seen in women of childbearing age, clinical manifestations of breast pain and swelling and more aggravated before menstruation, after menstruation can be relieved, when the pain is severe can be spread to the nipple, nipple pain. Third, acute mastitis, an acute purulent infection of the breast tissue, the clinical manifestations of which are redness, swelling, heat, pain, and visible milky white pus from the nipple secretion, may be combined with acute nippoconjunctivitis. Therefore, when there is painful nipple discomfort, you should go to the regular hospital breast surgery or general surgery in a timely manner, and should be clearly diagnosed by breast ultrasound, and then be evaluated by a professional physician to decide whether to perform conservative drug treatment or surgery.