Physiological causes 1. Healthy people who check transaminases after strenuous exercise will find elevated transaminases, sometimes accompanied by elevated creatine creatinase. 2.Overexertion can lead to elevated transaminases. 3.If you have eaten fatty food or alcohol before the test, it will lead to elevated transaminase, mostly accompanied by high transpeptidase. 4.People who are pregnant, in the middle and late stages of pregnancy, make transaminases elevated;, if it is too high, pay attention to whether there is gestational fatty liver. 5.Inadequate nutrition Irrational diet structure such as low protein diet, especially when the food is lack of cystine, vitamin E, can also make ALT elevated. Pathological causes 1, viral hepatitis. 2.A variety of drugs and chemical agents can cause high transaminases, i.e., drug-related hepatitis and toxic hepatitis. 3.Cirrhosis 4.Hepatocellular carcinoma, usually will appear high transaminases. 5.Biliary tract diseases such as cholecystitis and cholelithiasis in acute attack, as biliary origin liver injury. Common in the bed are cholecystitis, bile duct ascariasis, hepatobiliary stones, gallbladder and bile duct tumors, cancer around the jugular abdomen, congenital bile duct dilatation, acute and chronic pancreatitis, pancreatic headache, and hemorrhagic necrotizing pancreatitis. 6, heart disease: acute myocardial infarction, myocarditis, heart failure, can cause high transaminases. 7, certain infectious diseases,: in addition to the liver, other organ tissues in the body such as heart, kidney, lung, brain, testes, muscle also contain this enzyme. Therefore, when patients with myocarditis, pyelonephritis, lobar pneumonia, tuberculosis, polymyositis, hyperthyroidism, acute sepsis, enteric typhoid, rheumatism, malaria, leptospirosis, influenza, measles, schistosomiasis, extrusion syndrome, etc., can also be seen in the blood transaminases elevated. 8, young women should also pay attention to the possibility of autoimmune hepatitis, check whether the autoimmune antibody (anti-nuclear antibody, anti-smooth muscle antibody, etc.) is positive; 9, whether there are previous diseases such as cholecystitis, heart disease, nephritis, these diseases can also cause transaminases to rise.