If the restlessness, rumination, and insomnia have lasted for a relatively long period of time, and if the liver and kidney function and ECG tests are all fine, some pharmacological interventions can be considered. Because the state of anxiety can cause these manifestations above, at this time you can choose mirtazapine, amitriptyline, doxepin and other drugs to intervene. In addition, you can exercise moderately, a state of exercise to improve, we think it is also helpful. Such a drug treatment plan is best given by a specialist, because the doctor may need to consider the choice of specific drugs based on the overall physical condition, body type, etc.