Patients with irritable mood and insomnia are mainly treated symptomatically, starting with an outpatient visit to a psychiatric psychiatry clinic. If there is anxiety, sedative and sleeping drugs can be used to improve the symptoms, such as the use of lorazepam, eszopiclone, diazepam and so on. At the same time, the use of antidepressants, such as substances like paroxetine, mirtazapine, sertraline can be used to control the patient’s anxiety problem, and insomnia will then improve. If the patient’s anxiety is not obvious, and there is irritability and insomnia, we should focus on adjusting in spiritual and psychological aspects and relaxing our mind. You can improve the symptoms through some treatment, or a combination of Chinese and Western medicine, which can make the drugs to ease the liver and relieve depression, such as Shu Liver Relief Capsules, Baile Sleep Capsules, Sweet Dream Capsules, with acupuncture to improve the symptoms.