Diabetes can develop neurological complications, also known as neurological comorbidities, the most common of which is diabetic peripheral neuropathy. Peripheral neuropathy is symmetrical, but the lower extremities are more severe than the upper extremities, and the disease progresses relatively slowly, with abnormal peripheral sensations in the extremities, such as burning, swelling, and itching, all of which are neurological complications of diabetes. In addition, neuropathic pain, motor neuron involvement, muscle weakness, and muscle atrophy may also occur. Severe neurological complications of diabetes mellitus include hyperactive tendon reflexes, which may be weakened or even disappear in severe cases.