How long one can live after gastrectomy depends on one’s physical condition and the severity of the disease, and there is no specific time standard. The stomach is the digestive organ of the human body, and the biggest impact is the digestive function of the human body after the resection. Some patients who have gastric resection because of stomach lesions such as gastric cancer mainly rely on the small intestine to digest food, and their digestive speed and ability will be worse than before, but they are still able to absorb and supplement the body’s needs normally. Gastrectomy may lead to iron deficiency anemia, which can be supplemented by oral iron supplements. Reflux esophagitis will also occur. After total gastrectomy, bile will easily reflux into the esophagus, which can be treated with oral medication to protect the esophageal mucosa and gastrointestinal dynamics. Malignant tumors of the stomach leading to gastrectomy, such as gastric cancer, have a 5-year survival rate of 92.6%, 76.2%, 40.8%, and 6% for stages I, II, II, and IV, respectively. The 5-year survival rate after radical gastrectomy is 60.2%. Total gastrectomy patients need to make dietary adjustments, such as eating smaller meals, eating easily digestible food, actively improving nutritional status, and preventing esophagitis and dumping syndrome. If discomfort occurs, it is necessary to actively consult the doctor and follow the doctor’s instructions for reasonable treatment.