Toxoplasmosis, also known as toxoplasmosis, is a zoonotic disease caused by Toxoplasma gondii. The clinical manifestations of the disease are complex, and the symptoms and signs are not specific enough to cause misdiagnosis, mainly affecting the eyes, brain, heart, liver, lymph nodes and so on. After a pregnant woman is infected, the pathogen can infect the fetus through the placenta, directly affecting fetal development and causing serious teratology. Congenital toxoplasmosis is usually caused by acute toxoplasmosis (often asymptomatic) in pregnant women during pregnancy. Prospective studies have shown that the incidence and severity of congenital infections are related to the timing of the infection in pregnant women: in pregnant women infected with Toxoplasma gondii in early pregnancy, if they do not receive treatment, 10%-25% of congenital infections can lead to spontaneous abortion, stillbirth, preterm birth and severe neonatal infections; in pregnant women infected in mid- and late pregnancy, 30%-50% (72-79% of which can be asymptomatic) and 60-65% (89% of which can be asymptomatic) of congenital infections, respectively. 60-65% (of which 89%-100% can be asymptomatic) of fetal infections. The incidence of congenital infection can be reduced by about 60% if infected pregnant women are treated. The clinical presentation of congenital toxoplasmosis varies. Most infants can be born asymptomatic, and some of them develop retinal chorioretinitis, strabismus, blindness, epilepsy, anencephaly, intracranial calcification, adrenal agenesis, polycystic kidney, congenital malformation, psychomotor or mental retardation in the months or years after birth. Prevention methods: First, serum antibody test should be performed in early pregnancy, and if TORCH is negative (i.e., not infected), attention should be paid to prevention of infection and regular review; once acute infection is found in pregnant women, active treatment should be given, and amniocentesis and ultrasound examination of the fetus should be performed at the same time. If the fetus is found to have obvious disease, the parents may consider terminating the pregnancy. Second, pay attention to dietary hygiene, and meat should be fully cooked. Third, stay away from pets. Fourth, pay attention to daily hygiene and wash your hands carefully if you come in contact with animal excrement.