If hepatitis B is not combined with cirrhosis of the liver, there is usually no obvious change in the blood routine, if combined with cirrhosis of the liver, it may be manifested as a decrease in red blood cells, white blood cells or platelets. Hepatitis B is mainly caused by infection of hepatitis B virus and a kind of infectious disease, this disease in the early stage of the test blood routine is usually no special abnormality, if progressed to the stage of cirrhosis of hepatitis B, in the examination of blood routine often suggests that the three series of reduction, indicating the existence of splenic hyperfunction, that is to say, suggests that the white blood cell count, platelet count, red blood cell count will be declined progressively. People infected with hepatitis B should be regularly rechecked every three months or half a year or so for liver function, hepatitis B dna quantification, abdominal ultrasound, elasticity ultrasound, alpha-fetoprotein, renal function, blood glucose, blood lipids, blood routine and other conditions. Patients should pay attention to not stay up late, do not drink alcohol, do not take drugs casually, do not eat pickled products.