Sindelic acid drug refers to sindelic acid monoclonal antibody injection, does not belong to the chemotherapy drugs, the use of the drug after treatment of numbness of the limbs, legs, weakness is mostly caused by side effects of the drug, generally minor does not require special treatment, serious cases of feasible nutritional nerve, rehydration, desensitization and other symptomatic treatment. When there is a malignant tumor disease, patients may need to choose Sindilizumab injection drug for immunotherapy. However, these drugs are prone to side effects on the body, resulting in the presence of symptoms such as numbness of the limbs and weakness of the legs. Under normal circumstances, there is no need for special treatment of the above symptoms, patients stop using the above drugs in time, numbness of the limbs and other symptoms can disappear on their own, according to the specific conditions of the seriousness of the disease can be carried out nutritional nerve such as endogenous vitamin B12, rehydration, desensitization, such as dexamethasone and other symptomatic treatment. Patients with numbness of the limbs and weakness of the legs after the use of Sindilizumab injection should go to the hospital in time to clarify the specific causes of the situation.