According to the follow-up of CIN3 patients, the cure rate of cervical conization can reach more than 90%, and a few women have persistent lesions or recurrence or even further development after conization. CIN3 is a precancerous lesion that has not yet progressed to cancer, and cervical conization can achieve a better therapeutic effect. The cure rate is related to the status of the margins, and if the postoperative pathology returns negative margins, the cure rate may reach more than 90%. Most women can achieve positive margins after treatment and have a good outcome. A small percentage of women report positive margins on pathology after conization, indicating inadequate surgical coverage and the need for supplemental surgical treatment. Specific treatment options need to be selected in conjunction with nuclear magnetic and other tests, and can be supplemented with conization or cervical resection, or even hysterectomy, with regular follow-up and observation after surgery. Therefore, regular follow-ups with TCT and HPV tests as prescribed by the doctor are needed after the surgery to detect changes in the condition and treat it in time.