Cranial repair is a routine surgery in neurosurgery, which is performed to repair cranial defects caused by various reasons, with the aim of restoring the cranial cavity to complete closure, providing a stable intracranial environment, improving the intracranial cerebrospinal fluid circulation, blood circulation, etc., and providing a guarantee for the normal functioning of all neurological functions and even the life of the whole body. Cranial repair has a very long history, as our ancestors were practicing such surgery thousands of years ago. After a long history of development and evolution, cranial repair has become very routine and technically mature in the present medical conditions and environment. As the technology has evolved, the materials used for cranial repair have also undergone constant change and innovation. The materials used in the past, such as flannel, animal bone, autologous bone, calcium phosphate bone cement, hydroxyapatite, plexiglass, silicone, acrylic, etc., have all been withdrawn from the historical stage due to various problems. The more widely used cranial bone repair material in clinical practice at present is the material of titanium mesh. This titanium mesh is progressive compared to the more traditional materials of the past. However, there are still some defects and shortcomings of titanium mesh, and various problems may occur in clinical use, such as postoperative infection and rejection. Some patients ask how long is the rejection period of titanium mesh for skull repair? This rejection period is not fixed, some people may have rejection reaction within a short time after surgery, while some people may have rejection after several years or even more than ten years. In addition to the infection rejection, the titanium mesh material may also produce some other problems, such as its covering repair, which may wear the scalp, causing scalp breakage and material exposure; for example, this metal material is not insulated, which may cause postoperative patients to be more sensitive to the external environment of hot and cold, causing discomfort; this metal material may also interfere with the magnetic field and radiation projection, affecting postoperative patients to receive ct MRI; in addition, because this material is not hard enough, it is easy to deform and collapse if it is subjected to external force after surgery …… so it is not recommended to use titanium mesh for skull repair at present. At present, our team adopts a new polyetheretherketone peek material with more excellent performance for skull repair, which has achieved good results in clinical practice. Polyetheretherketone is a new type of special polymer material, and its various properties are very close to human autologous cranial bone, which well overcomes the various problems that may arise from titanium mesh as mentioned above. The team not only uses this advanced material, but also constantly carries out technical improvement and innovation and material optimization design, and introduces the concept of cosmetic plastic surgery, so as to carry out peek cranial repair and plastic surgery comprehensively, achieving good results of anatomical integrity, perfect function and beautiful appearance, which are widely praised and recognized by patients and families.