Liver palms should be treated with hepatoprotective drugs and antiviral drugs in order to restore liver function. Liver palms usually refer to the phenomenon of flaky blood congestion at the intervals between the thumb and the root of the little finger in the palm of the hand due to the dilation of small arteries caused by the accumulation of estrogen in the body after liver disease leading to liver dysfunction. Liver-protecting drugs can be used under doctor’s guidance to improve liver function, such as silymarin capsules, turtle shell soft liver tablets, diammonium glycyrrhizinate capsules, bisacodyl tablets, etc. Antiviral drugs, such as entecavir, tenofovir, etc. can be used with a view to reversing hepatic fibrosis and improving the symptoms of the liver palms. While treating liver palms, it is also necessary to improve relevant examinations with the help of doctors, such as blood biochemistry, ultrasound, imaging, liver pathology, etc., to clarify the liver disease and carry out targeted treatment.