Early stage of liver cancer often has no obvious symptoms, and when it develops to a certain stage, it may cause nail flaking, white color of nails and nail depression due to anemia and lack of microelements. Early stage of liver cancer lacks typical clinical manifestations, and once symptoms and signs appear, the disease has already entered the middle or advanced stage. Common clinical manifestations of liver cancer include persistent swelling and pain or dull pain in the right upper abdomen, enlarged liver, yellowish skin, lethargy and decreased appetite. Digestive symptoms such as decreased appetite, abdominal distension and nausea often lead to insufficient energy intake, anemia and micronutrient deficiencies, resulting in changes such as whitening of nails, flaking, and depressions of nail beds. However, whitening and flaking of nails are not always caused by liver cancer, and simple malnutrition can also cause nail changes. Therefore, if your nails show symptoms different from those in the past, you should go to the hospital in time, complete the relevant examinations, and identify the cause of the disease before giving targeted treatment.