Sequelae of neocoronaviruses may have cerebral atrophy, but authoritative literature and clinical data cases are lacking. Although some studies have shown that in experiments on some cases of neocoronavirus pneumonia, it was found that neocoronavirus has considerable effects on the brain, which includes brain atrophy, and thus similar statements have appeared. However, the fact that the experimental data cannot be directly applied to the clinic does not mean that this conclusion is completely correct. There is no authoritative literature or clinical case statistics that can prove the authority of this view. And most of the cognition for the sequelae of the new crown for the respiratory system, the digestive system, the nervous system, whether to produce brain atrophy still need to later case statistics and experiments, can not be directly recognized. Tip: “New coronary pneumonia and new coronary virus pneumonia” mentioned in this article have been renamed to “new coronary virus infection” on December 26, 2022, as announced by the National Health Commission.