Diagnostic criteria for polycystic ovary syndrome

Polycystic ovary syndrome can be diagnosed by clinical symptoms, ultrasound examination, endocrine measurement, etc., and other diseases that may cause similar symptoms should be ruled out, mainly the following diagnostic methods and criteria: 1. Clinical features include hirsutism, acne, etc.; 3. Acanthosis nigricans: gray-brown pigmentation, symmetrical, thickened skin, soft texture in the skin folds of labia, back of neck, axilla, under breast and groin. Ultrasound examination: polycystic ovaries with ≥12 follicles of 2-9 mm in diameter and/or ovarian volume ≥10 mL, sporadic ovulation or anovulation. Endocrine measurements: 1. serum androgens: testosterone level usually does not exceed 2 times the upper limit of the normal range, androstenedione is often elevated; 2. folliculopoietin (FSH) and luteinizing hormone (LH): FSH is normal or low, LH is elevated, LH/FSH ≥ 2-3; 3. serum estrogens: estrone (E1) is elevated, estradiol (E2) is normal or mildly elevated, E1/E2 > 1, higher than normal cycle; 4. 1, higher than normal cycle; 4, urinary 17-ketosteroids: normal or mildly elevated, suggesting androgenic origin from ovaries when normal, and hyperadrenalism when elevated; 5, serum prolactin (PRL): 20%-35% of patients may have mildly elevated serum PRL; 6, anti-müllerian hormone (AMH): serum AMH is mostly 2-5 times higher than normal. IV. Other: exclude other diseases that may cause hyperandrogenism or abnormal ovulation, such as hyperprolactinemia and pituitary tumor.