To determine whether it is pleurisy, we need to combine clinical symptoms, etiology, relevant examination results and other circumstances to consider. Pleurisy is a common inflammatory disease that occurs in the pleura of the human thoracic cavity, due to various pathogenic microorganisms that invade the pleura in different ways, triggering an inflammatory reaction, which is mainly characterized by chest tightness, chest pain, dyspnea and other discomforts, and most of them are treated with internal medicine, while a few require surgical treatment. The diagnosis of pleurisy relies on clinical manifestations and a history of infectious or traumatic disease, supplemented by results of chest CT, routine biochemistry of pleural effusion, and routine blood tests. Most cases of pleurisy are associated with other diseases, and require specialized treatment in a specialized department after evaluation by a specialist.