Cramps can be seen in hypocalcemia, epilepsy, recovery from cerebral infarction, extrapyramidal disorders, and after strenuous exercise. 1. Hypocalcemia: It is due to low blood calcium concentration, which stimulates the muscles, resulting in muscle twitching. 2. Epilepsy: It is due to abnormal discharge of localized brain nerve cells, which leads to twitching of one side or the whole limb. 3. Recovery from cerebral infarction: after cerebral infarction, there will be elevated muscle tone in the limbs, which may lead to the phenomenon of one side of the limb twitching. 4. Extrapyramidal disease: It is due to the damage of the brain regulator motor function area, which leads to inflexibility of the patient’s activities, accompanied by abnormal activities. 5. Strenuous activities, patients with a lot of sweating will lead to metabolic disorders of the patient’s electrolytes, there may be low sodium, low potassium, low calcium and so on, leading to the emergence of limb cramps. In short, there are many conditions that lead to cramps in the limbs of patients, and it is necessary to consult a doctor in time to identify the cause of the disease and treat the cause of the disease.