Prednisolone acetate tablets alone can not lower creatinine, it is recommended that patients follow the doctor’s instructions for medication. Prednisolone acetate tablets belong to hormone drugs, with anti-inflammatory, anti-allergy, anti-rheumatism, etc.; clinically commonly used in allergic diseases, serious infections, autoimmune diseases, etc., the condition is stabilized gradually reduce the amount of the drug, the drug did not improve the symptoms recommended to the hospital. Elevated creatinine may be related to renal insufficiency, it is recommended that the patient to improve further examination, in the clear creatinine elevation of the etiology and then in the guidance of the physician reasonable treatment, hormone drugs can not be abused, long-term use of high-dose easy to cause muscle weakness and muscle atrophy, thinning of the skin, centripetal obesity, osteoporosis, and other adverse reactions. Allergic to steroid hormones and contraindicated during pregnancy, patients must follow the doctor’s instructions to use, so as not to lead to adverse consequences, in addition, patients with elevated creatinine can also be intervened through the control of diet and body weight and so on.