The sebum secretion can be controlled by the following methods: 1, dietary regulation, do not eat sweets, fried foods, strong tea, coffee and spicy food, eat more fresh vegetables and fruits; 2, retinoids, oral isotretinoin capsules, can inhibit sebaceous secretion; 3, estrogen, oral daing-35, can counteract the effect of increased androgen secretion; 4, vitamins, supplement B vitamins, such as vitamin B2, vitamin B6, etc., can reduce oil secretion; 5, do not stay up late, maintain sufficient sleep.